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EC number: 205-633-8
CAS number: 144-55-8
No data on reproduction toxicity were
available. However, based on the normal physiological role of sodium and
bicarbonate no toxicity on mammalian reproduction is expected. No
further study is considered necessary for this endpoint.
An oral developmental study was performed
in 3 species (mouse, rat and rabbit). In all three species no maternal
or teratogenic effects were noted, and NOAEL 's were above highest dose
Sodium bicarbonate did not induce
developmental effects when administered orally at the following doses:
580 mg/kg bw (mice), 340 mg/kg bw (rats) and 330 mg/kg bw (rabbits).
Furthermore the substance will usually not reach the foetus when the
exposure to sodium bicarbonate is sufficiently low, as it does not
become systemically available.
taken from OECD SIDS on sodium bicarbonate (2002), pg.18]
Based on the available
information, the substance does not need to be classified according
Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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