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EC number: 205-633-8
CAS number: 144-55-8
- Concentration / response curve:
Mean percentage mortality (of vessel A and B) after 96 hours:
Control: 5 %
630 mg A.I./L: 0 %
1100 mg A.I./L: 0 %
1800 mg A.I./L: 5 %
3100 mg A.I./L: 0 %
5400 mg A.I./L: 100 %
- Effect concentration vs. test substance solubility: Not reported
- Other effects: Not reported
RESULTS CONTROL: No effects
was conducted exposing for 48-hr flow-through test the water flea, Daphnia
magna, to NaHCO3 at concentration ranging from 780 to
6,000 mg/L, following the EPA OPP 72-2 “Aquatic Invertebrate Acute
Toxicity Test” guideline. Results showed a NOEC of 3,100 mg/l and a LC50
of 4,100 mg/l.
Only one study was performed by GLP standard (Putt, 1993) is available and so it was chosen as key study. Putt (1993) studied, in a 48-hr acute flow-through test, Daphnia magna exposed to NaHCO3at concentration ranging from 780 to 6,000 mg/L, following the EPA OPP 72-2 “Aquatic Invertebrate Acute Toxicity Test” guideline. Results showed a NOEC of 3,100 mg/l and a LC50 of 4,100 mg/l.
Two reliable (K 2) studies (Hoke et al., 1992 and Mount et al.,1997) reported in the OECD SIDS (2002) on sodium bicarbonate, exposed the cladocera, Daphnia magna and Ceriodaphnia sp, for 48h to NaHCO3. Results showed a EC50 for immobilization of 1,268-1,640 mg/l and 1,020-1,268 mg/L, respectively.
Furthermore, a reliable publication (Harper et al., 2014) was available reporting data on 5 different invertebrates: the chironomid Chironomus dilutus (7 -14 dph); the worm Tubifex tubifex (adults); the amphipod Hyalella azteca (adults); the freshwater mussel Lampsilis siliquoidea (newly transformed juveniles) and water flea Ceriodaphnia dubia (neonates). Test were conducted following the EPA guideline 821/R-02/012 “Methods for measuring the acute toxicity of effluents and receiving waters to freshwater and marine organisms, 5th ed”, with the exception of ASTM International E2455-06 “Standard guide for conducting laboratory toxicity tests with freshwater mussels ”for experiments with mussels. Experiments were run in 2 different medium, reconstituted Tongue river water and reconstituted Powder river water for all the species, with exception of test with mussels which were run only in reconstituted Tongue river water. Results showed a LC50 ranging from 989 to 8,014 mg/L NaHCO3, depending on the species and the medium used.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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