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EC number: 205-633-8
CAS number: 144-55-8
LOAEL: 29 g/l. The intention with the study was to examine the mechanisms by which the dietary buffers widely used in livestock production excert their effect. Specifically the influence of ruminal infusion of various amount of NaHCO3 on ruminal and systemic acid-base status and mineral metabolism. Infusion of buffer increased ruminal fluid buffering capacity transiently at 4.5 hrs post-feeding but otherwise did not markedly affect ruminal acid-base status. Systemic acid-base status was unaffected by the buffer primarily because renal excretion of base succesfullyreduced systemic base load. Urine volume increased in response to NaHCO3 infusion. Buffer infusion increased urinary excretion of Na, Mg, and K but decreased Ca excretion for 12 hrs post feeding; Cl excretion was not affected. Buffer infusion tended to increase total volatile fattyacids in ruminal fluid. The authors' data indicate that homeostatic mechanisms can eliminate exogenous base via the kidneys; hence, acid-basestatus was not perturbed by infusion of NaHCO3. The authors further claim that increased excretion of Mg and K with buffer infusion indicates that the dietary requirements for these minerals may be increased by NaHCO3. The diuresis accompanying large doses of NaHCO3 may increase dietary requirements for some minerals. There was little effects on milk production or composition.
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