Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-633-8
CAS number: 144-55-8
LOAEL: 29 g/l. The intention with the study was to examine the mechanisms by which the dietary buffers widely used in livestock production excert their effect. Specifically the influence of ruminal infusion of various amount of NaHCO3 on ruminal and systemic acid-base status and mineral metabolism. Infusion of buffer increased ruminal fluid buffering capacity transiently at 4.5 hrs post-feeding but otherwise did not markedly affect ruminal acid-base status. Systemic acid-base status was unaffected by the buffer primarily because renal excretion of base succesfullyreduced systemic base load. Urine volume increased in response to NaHCO3 infusion. Buffer infusion increased urinary excretion of Na, Mg, and K but decreased Ca excretion for 12 hrs post feeding; Cl excretion was not affected. Buffer infusion tended to increase total volatile fattyacids in ruminal fluid. The authors' data indicate that homeostatic mechanisms can eliminate exogenous base via the kidneys; hence, acid-basestatus was not perturbed by infusion of NaHCO3. The authors further claim that increased excretion of Mg and K with buffer infusion indicates that the dietary requirements for these minerals may be increased by NaHCO3. The diuresis accompanying large doses of NaHCO3 may increase dietary requirements for some minerals. There was little effects on milk production or composition.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again