Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-633-8
CAS number: 144-55-8
In accordance with section 1 of REACH Annex
XI, the study does not need to be conducted as the uptake of sodium, via
exposure to sodium bicarbonate, is much less than the uptake of sodium
via food. Therefore, sodium bicarbonate is not expected to be
systemically available in the body. Furthermore, it should be realised
that an oral uptake of sodium bicarbonate will result in a
neutralisation in the stomach due to the gastric acid. Sodium
bicarbonate is an important extracellular buffer in vertebrates and is
therefore readily regulated in the body.
study is available exposing
Hy-line brown hens for up to 50 weeks to a diet supplemented with 3 g/kg
of NaHCO3. The study was conducted following the Guidelines
for Experimental Animal Research of the Ministry of Science and
Technology, P. R. China. Results showed no adverse effect on feed
consumption and efficiency and eggs masses compared with the control,
determining a NOEC of 3 g/kg diet. After 50 weeks, 75 weeks hens showed
a significant lower eggshell thickness and strength compared with the
control, determining a LOEC of 3g/Kg diet. In contrast, eggs production
was stimulated significantly with exposure to the test item.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Esta web utiliza cookies para mejorar su experiencia de navegación en nuestros sitios web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again