Registration Dossier
Registration Dossier
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EC number: 205-633-8 | CAS number: 144-55-8
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Two reliable studies are available reporting results on exposure to NaHCO3 for three different species: Daphnia magna (Leblanc and Surprenant, 1984), Ceriodaphnia dubia (Farag et al., 2013) and Lampsilis siliquoidea (Farag et al., 2013).
Leblanc and Surprenant (1984) was described already on page 20 of the OECD SIDS dossier (2002). Please find hereafter the text:
Leblanc and Surprenant (1984) carried out a (chronic) reproduction test with D. magna. Test solutions were prepared to contain the appropriate concentrations of salts to yield a total hardness of 170 mg/l CaCO3 (USEPA 1975). At the tested concentration sodium bicarbonate of 576 mg/l the survival was 100% and the cumulative number of offspring per female did not significantly differ from the control. This demonstrates that the 21-day Daphnia magna NOEC is higher than 576 mg/l. Although the study is not carried out according to OECD 202, it is very well described.
Farag et al. (2013) conducted a study exposing neonate of the water flea, C. dubia, for 7 days to a concentration range of 500-1500 mg/L of NaHCO3. The study was conducted following the EPA guideline EPA 600/4-91/002 “Short term methods for estimating the chronic toxicity of effluents and receiving waters to aquatic organisms” and the validity criteria of the test were satisfied. Results showed a LC50 of 1192 mg NaHCO3/L and IC20 for reproduction of 359 mg NaHCO3/L. Furthermore, newly transformed freshwater mussels, L. siliquoidea, were also exposed in a separated experiment for 10 days to a concentration range of 500-2000 mg/L of NaHCO3. The study was conducted following the ASTM guideline E 2455-06 “Standard guide for conducting laboratory toxicity tests with freshwater mussels”. Results showed an EC50 and an IC20 for immobilization of 1061 mg NaHCO3/L and 952 mg NaHCO3/L, respectively.
Key value for chemical safety assessment
Additional information
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