Registration Dossier
Registration Dossier
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EC number: 203-002-1 | CAS number: 102-06-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Etude expérimentale des effets physiologiques de la diphénylguanidine
- Author:
- Valade P, Delga J et Salle J
- Year:
- 1 949
- Bibliographic source:
- Comptes Rendus Soc. Biol. 143, 815-817
- Reference Type:
- secondary source
- Title:
- N,N'-Diphenylguanindine
- Author:
- Bayer E.
- Year:
- 1 992
- Bibliographic source:
- BUA Report 96 (august 1992). GDCh- Advisory Committee on existing chemicals of environmental relevance.
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- No detail available
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- 1,3-diphenylguanidine
- EC Number:
- 203-002-1
- EC Name:
- 1,3-diphenylguanidine
- Cas Number:
- 102-06-7
- Molecular formula:
- C13H13N3
- IUPAC Name:
- 1,3-diphenylguanidine
- Details on test material:
- No data
Constituent 1
Test animals
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No data
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: no data
- Details on inhalation exposure:
- For inhalation, animals (not precised) were exposed in inhalation chamber during 30 min.
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 30 min
- Concentrations:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
- Details on study design:
- no
- Statistics:
- no data
Results and discussion
- Preliminary study:
- no data
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC0
- Effect level:
- >= 500 mg/m³ air (nominal)
- Exp. duration:
- 30 min
- Mortality:
- no data
- Clinical signs:
- other: At 500 mg/m3, after 30 min of exposition, animals showed a slightly hypnotic effect.
- Body weight:
- no data
- Gross pathology:
- no data
- Other findings:
- no
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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