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EC number: 203-002-1
CAS number: 102-06-7
study evaluates DPG for its ability to induce forward mutation in the
L5178Y TK+/- mouse lymphoma cell line, as assessed by colony growth in
the presence of 5-bromo-2'-deoxyuridine (BrdU). DPG did not induce a
significant increase in mutations at the TK locus in L5178Y mouse
lymphoma cells at applied concentrations of 16.4 to 188.0 ug/ml without
activation and at 32.8 to 525 ug/ml with microsomal activation. These
concentration ranges included highly toxic treatments. Therefore, the
test compound is considered to be inactive in the Mouse Lymphoma Forward
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