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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

According to a GLP OECD (301D) study, 1,3-diphenylguanidine is readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

A number of reported data were available on 1,3-diphenylguanidine from 1960 to 1988. However, data assessment was difficult because the studies were poorly documented. In two studies (Chou et al., 1983 ; Kondo, 1988), DPG was for example noted as rapidly degraded in non-adapted river water but no sound biodegradation follow-up was performed. In addition, the results of Saegar et al. (1988) suggested that the test item could be readily biodegradable. That is the reason why a full GLP OECD 301D study was commissioned in 2015. This study showed that DPG is readily biodegradable and that no persistent metabolite can be expected.