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EC number: 203-002-1
CAS number: 102-06-7
An acute oral toxicity study of 1.3
-diphenylguanidine was conduted using Crj:CD(SD)IGS rats with five males
and five females in each group.
DPG was suspended in corn oil, and single
forced oral administration of 50 -143 mg/kg was conducted on both sexes.
A solvent control group was established, with administration of only
corn oil. The observation period was 14 days, and then observations were
made on the mortality, toxicity and period of onset, changes in weight,
and pathological examinations were also concluded.
The LD50 value was 111 mg/kg for males and
107 mg/kg for females.
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