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Long-term toxicity to fish

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Description of key information

no experimental data available

Key value for chemical safety assessment

Additional information

In Annex IX of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity to fish shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on fish. According to Annex I of this regulation, the chemical safety assessment triggers further action when the substance or the preparation meets the criteria for classification as dangerous according to Directive 67/548/EEC or Directive 1999/45/EC or is assessed to be a PBT or vPvB.

Reaction mass of 2 -piperazin-1-ylethanol, piperazine-1,4 -diethanol, piperazine: The ACR approach according to ECETOC (2003, Report no. 91) results in NOECs greater than 1 mg/L based on the effect data for pH-adjusted and pH-unadjusted test solutions. The hazard assessment of the reaction mass reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment. Therefore and for reasons of animal welfare a long-term toxicity test in fish is not provided.