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Description of key information

Piperazine is neurotoxic to humans. Piperazine is a skin- and respiratory sensitiser to humans.

Additional information

Through its use as an anti-helmintic agent, neurotoxic effects have been noted in humans, both after single dose exposure and repeated doses.

Skin sensitising reactions has been noted among humans exposed to piperazine, and also respiratory sensitisation among workers exposed to piperazine.