Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information


After evaporation or exposure to the air, the reaction mass will be rapidly degraded by photochemical processes.



According to structural properties, hydrolysis is not expected.



The reaction mass of 2 -piperazin-1 -ylethanol, piperazine-1,4 -diethanol and piperazine (50, 25 and 25%) is assessed to be not readily biodegradable based on a weight-of-evidence approach.

Since the reaction mass or the majority of its components are neither considered as readily nor as inherently biodegradable, no significant degradation of the reaction mass is expected. However, there is some evidence that piperazine may be considered as readily biodegradable. Based on the available screening data significant biodegradation cannot be expected for the reaction mass in the environment. This finding is supported by the chemical structures of 2 -piperazin-1 -ylethanol and piperazin-1,4 -diethanol which indicate a low potential for biodegradation. Therefore, no further tests on biodegradation are performed because it is not expected that further testing will significantly change this assessment.



Accumulation in organisms is not to be expected.



Adsorption to the solid soil phase is not expected under environmentally relevant conditions.


Henry's Law Constant

From the water surface, the major components of the reaction mass will not evaporate into the atmosphere under environmentally relevant conditions.



Over time, the major components will preferentially distribute into the compartment water (>=99.1%).