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EC number: 947-726-2 | CAS number: -
After dermal administration of 10 mg (≈ 30μCi) 14C-labelled test substance to the back of each of four rabbits over a 5 x 8 cm area most of the radioactivity remained at the site of application (88 ± 2.3%). Only traces of administered radioactivity were detected over a 72 h-period in urine (0.15 %), faeces (0.16 %), exhaled carbon dioxide (0.27 %), other skin (0.2%) and cage wash (0.3%).
Based hereupon, the dermal absorption and the concentration of Dioctadecyldimethylammonium chloride in the skin can be assumed to be very low.
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