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EC number: 247-557-8
CAS number: 26264-06-2
animals showed a positive response at the 24 and 48 hr readings.
of Skin Sensitisation Study
0 hrs after challenge
24 hrs after challenge
48 hrs after challenge
group of 10 male and 10 female guinea pigs were used to determine the
potential of the test substance to be sensitising to skin. The animals
were first given an intradermal induction of 0.05% of test substance in
corn oil. One week later, they were given a dermal induction of 5% test
substance in corn oil. A group of 5 male and 5 female guinea pigs were
used as controls. These animals were treated in a similar fashion with
vehicle only. Two weeks after the dermal induction, a challenge was
performed via dermal exposure to 2.5% test substance in corn oil. The
control group was exposed as well. The animals were exposed for 24 hrs.
Skin irritation readings were made at 24 and 48 hrs after the end of
exposure. No positive responses were seen in either the test or control
group. The test substance is not sensitising to skin.
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