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EC number: 247-557-8 | CAS number: 26264-06-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- MSDS Rhodacal CA/70
- Author:
- Rhodia
- Year:
- 1 998
- Bibliographic source:
- Product Safety labs
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Defined oral LD50. Adapted from appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics, by the Association of Food and Drug Officials of the United States, 1965.
- GLP compliance:
- no
- Test type:
- acute toxic class method
- Limit test:
- no
Test material
- Reference substance name:
- Calcium dodecylbenzenesulphonate
- EC Number:
- 247-557-8
- EC Name:
- Calcium dodecylbenzenesulphonate
- Cas Number:
- 26264-06-2
- Molecular formula:
- C36H58CaO6S2
- IUPAC Name:
- calcium bis(2-undecylbenzene-1-sulfonate)
- Test material form:
- solid: compact
- Details on test material:
- - Name of test material (as cited in study report):Benzenesulfonic acid, dodecyl-, calcium salt
Benzenesulfonic acid, dodecyl-,calcium salt), purity 69-71%.
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- Rat (Sprague-Dawley), weight 200-300 g.
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- water
- Details on oral exposure:
- Single dose by oral gavage of 1.0, 1.5, 2.0, 2.5 and 3.0 mL/kg bw.
- Doses:
- 1.0, 1.5, 2.0, 2.5 and 3.0 mL/kg bw.
- No. of animals per sex per dose:
- 5/sex/dose group.
- Control animals:
- yes
- Details on study design:
- Mortality/clinical signs daily for 14 days. Body weight on day 0 and 14. Macroscopy on animals that died.
- Statistics:
- Litchfield-Wilcoxin (Probit analysis).
Results and discussion
Effect levels
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 1 300 mg/kg bw
- Based on:
- act. ingr.
- Mortality:
- Motaliity was not affected.
- Clinical signs:
- other: A high incidence of diarrhea was noted with the use of the higher concentration. Those rats which succumbed appeared to be weak and showed reduced voluntary activity prior to death.
- Gross pathology:
- No significant gross abnormalities were seen at autopsy.
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- The acute oral LD50 in male/female rats is 1300 mg/kg bw. No significant gross abnormalities were seen at autopsy.
LD50-rat 1.8 mL/kg ⇔ 1.3 g a.i./kg = 1300 mg/kg bw - Executive summary:
The acute oral LD50 in male/female rats is 1300 mg/kg bw. No significant gross abnormalities were seen at autopsy.
LD50-rat 1.8 mL/kg ⇔ 1.3 g a.i./kg = 1300 mg/kg bw
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