Registration Dossier

Administrative data

Endpoint:
additional ecotoxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Non-guideline study addressing non-standard endpoints. Unclear if stoppered containers were used and if nominal concentrations were maintained.

Data source

Reference
Reference Type:
publication
Title:
Cytotoxicity of 109 chemicals to goldfish GFS cells and relationships with 1-octanol/water partition coefficients
Author:
Saito, H., Koyasu, J., Yoshida, K.
Year:
1993
Bibliographic source:
Chemosphere, 1993, 26(5), 1015-1028

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
In vitro cytotoxicity study of goldfish scale cells. Survey of the toxicity of 109 chemicals and their relationship with the logPow. Details on the method published separately (Saito, H., Iwami, S., Shigeoka, T., Chemosphere, 1991, 23, 525-537).
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

Midpoint cytotoxicity, 24 hours, NR50=20g/L

Applicant's summary and conclusion