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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways


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Administrative data

Link to relevant study record(s)

Description of key information

Hydrolysis is not expected under environmentally relevant conditions (pH 5 - 9).

Key value for chemical safety assessment

Additional information

Primary and secondary ethers are relatively inert to most reagents, including strong bases, reducing agents, and weak acids (Streitwieser A. et al, Introduction to Organic Chemistry, 4th Ed., Macmillan, 1992, p233). They do react with hot concentrated strong acids such as HBr and HI; however, these conditions are not environmentally relevant. Hydrolysis is not expected under relevant environmental conditions.