Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Does not meet important criteria of todays standard methods

Data source

Reference
Title:
Unnamed
Year:
1927

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
IUCLID4 Test substance: no data

Test animals

Species:
cat
Sex:
female

Administration / exposure

Route of administration:
subcutaneous
Vehicle:
unchanged (no vehicle)
Doses:
approx. 125 and 305 mg/ kg bw (single injection site)
in a second test a total dose of 125 mg/kg bw was injected at 8 different sites
No. of animals per sex per dose:
1 female cat per dose
Control animals:
no

Results and discussion

Effect levels
Dose descriptor:
other: lethal dose
Effect level:
305 mg/kg bw
Remarks on result:
other: approximate dose

Applicant's summary and conclusion