Registration Dossier

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given (comparable to guidelines/standards)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Quantitative structure-activity relationships and mixture toxicity studies of chloro- and alkylanilines at an acute lethal toxicity level to the guppy (Poecilia reticulata)
Author:
Hermens J, Leeuwangh P, Musch A
Year:
1984
Bibliographic source:
Ecotoxicology and Environmental Safety 8, 388-394
Reference Type:
other: BUA Report
Title:
Unnamed
Year:
1991
Reference Type:
publication
Title:
Quantitative structure-activity relationships in fish toxicity studies
Author:
Koenemann H
Year:
1981
Bibliographic source:
Toxicology 19, 209-221

Materials and methods

Principles of method if other than guideline:
open system (but covered with glass plate), semi-static
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test solutions

Vehicle:
yes
Details on test solutions:
stock solution in 2-propanol;
standard test water according to Alabaster and Abram

Test organisms

Test organisms (species):
Poecilia reticulata
Details on test organisms:
age: 2-3 months;
feeding: daily

Study design

Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
14 d

Test conditions

Hardness:
25 mg/L (CaCO3)
Test temperature:
22 +/- 1 °C
Dissolved oxygen:
<5 mg/L
Details on test conditions:
standard test water according to Alabaster and Abram;
open test system (but covered with a glass plate;
daily water renewal;
more details on test conditions: see Koenemann (1981)

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
6.25 mg/L

Applicant's summary and conclusion