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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
other: BUA report
Adequacy of study:
other information
Reliability:
other: BUA report
Rationale for reliability incl. deficiencies:
other: BUA report

Data source

Referenceopen allclose all

Reference Type:
other: BUA Report
Title:
Unnamed
Year:
1991
Reference Type:
publication
Title:
Toxicity, biodegradability, and accumulation of a number of Cl/N-containing compounds for classification and establishing water quality criteria
Author:
Canton JH, Slooff W, Kool HJ, Struys J, Pouw TJM, Wegman RCC, Piet GJ
Year:
1985
Bibliographic source:
Regulatory Toxicology and Pharmacology 5, 123-131
Reference Type:
publication
Title:
The list of the existing chemical substances tested on biodegradability by microorganisms or bioaccumulation in fish body by CITI
Author:
MITI (Ministry of International Trade and Industry)
Year:
1987
Bibliographic source:
pages 14 and 21, January 1987
Reference Type:
publication
Title:
Unnamed
Year:
1982
Reference Type:
publication
Title:
Waterborne methylene bis(2-chloroaniline) and 2-chloroaniline contamination around Adrian, Michigan
Author:
Parris GE, Diachenko GW, Entz RC, Poppiti JA, Lombardo P, Rohrer TK, Hesse JL
Year:
1980
Bibliographic source:
Bull. Environm. Contam. Toxicol. 24, 497-503

Materials and methods

Principles of method if other than guideline:
BUA report
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chloroaniline
EC Number:
202-426-4
EC Name:
2-chloroaniline
Cas Number:
95-51-2
Molecular formula:
C6H6ClN
IUPAC Name:
2-chloroaniline

Results and discussion

Details on results:
BUA report

Any other information on results incl. tables

BUA report:

In one publication, the reported log Pow values of o-chloroaniline of 2.0 resulted in a calculated a bioconcentration factor of 20 and thus a weak bioaccumulation potential for free o-chloroaniline was indicated. The calculation was performed according to Ross and Welch (log BCF = 0.76 log Pow - 0.23).

A second publication reports a BCF of 4 from a Pow value of 1.92. This publication does not state to the calculation equation.

The MITI list categorizes o-chloroaniline to be not or weakly bioaccumulative in fish.

There is one indication that o-chloroaniline may be bound covalently to macromolecules in the muscle tissue of carp.

Applicant's summary and conclusion