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EC number: 938-793-9
CAS number: -
No clinical signs of toxicity were
observed although male rats receiving 3000 mg/kg experienced 4% weight
loss at 24 hours after test substance administration and female rats
receiving 3000 mg/kg experienced 2% weight loss at 48 hours.
There was no change in ploidy, effect
on mitotic index, or cell aberrations in response to treatment with API
83-11. Treatment with TEM caused the appropriate positive response.
for Read Across
and physico-chemical data show that Straight-Run Gas Oils are very
similar to VGOs/HGOs/Distillate Fuels. It is considered appropriate,
therefore, to read across from the Straight-Run Gas Oil data to
were no clinical signs of toxicity during the study, although male rats
receiving 3000 mg/kg experienced 4% weight-loss at 24 hours after test
substance administration, and female rats receiving 3000 mg/kg
experienced 2% weight-loss at 48 hours. The
positive control TEM induced the appropriate response. There
was no evidence of increased incidence of chromatid or chromosome gaps
and breaks, fragments, structural rearrangements, or ploidy in bone
marrow cells treated with straight-run middle distillate in comparison
study received a Klimisch score of 1 and is classified as reliable
without restriction because the study was conducted according or similar
to OECD 475.
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