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EC number: 938-793-9
CAS number: -
In an eye irritation study, four females and
five males were administered 0.1 mL of undiluted #2 home heating oil.
The test material was applied to the everted lower lid of the right eye
of each of the nine rabbits. The left eye served as the untreated
control. In one male and one female, the test eye was flushed for one
minute with distilled warm water 30 seconds after application. Ocular
lesions were scored at 24, 48, and 72 hours after treatment. Fluorescein
dye evaluation was used for the 24 hour scoring. Scoring was based on
the Draize technique.
Only one rabbit, in the unrinsed group,
exhibited minor conjunctival erythema at the 24 and 48 hour reading. All
other animals were normal. Under the conditions of this study and according
to EU regulations, the test material is not irritating to eyes.
This study received a Klimisch score of 1.
It is classified as reliable without restrictions because it was
conducted similar to guideline study OECD 405. .
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