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EC number: 938-793-9
CAS number: -
an acute inhalation toxicity study, groups of young adult Sprague-Dawley
rats (10 per sex) were exposed by inhalation route to naval distillate
for 4 hours at 2.3, 3.5, or 4.9 mg/L of aerosol. Animals
then were observed for 14 days.
had laboured breathing and nasal discharge, but survivors were normal by
study termination. Following exposure, animals in all groups lost
weight, but body weight at study termination indicated recovery. The
inhalation LC50 was determined to be 5.4 mg/L in males, 3.6 mg/L in
females, and 4.1 mg/L in combined sexes. The test material is classified
as harmful by inhalation according to EU criteria.
study received a Klimisch score of one and is classified as reliable
without restrictions because the study was GLP compliant and was
generally conducted according to OECD 403 guidelines.
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