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EC number: 938-793-9
CAS number: -
Table 1: Average dermal irritation scores
Primary Irritation Score: 3.83
In a skin irritation study New Zealand White
rabbits (3/sex) were tested with #2 Home Heating Oil (50% cat]) a
substance composed of vacuum gas oils/hydrocracked gas oils/distillate
fuels. The rabbits were exposed to 0.5 mL of test substance applied to
four shaved test area on the back (2 abraded and 2 intact) via a a gauze
patch. Gauze patches were secured with Saran wrap and Band-Aids and
wrapped with Conform elastic tape. After 24 hours of exposure the
covering were removed and the test sites were wiped with gauze sponges
to removed excess material. Animals were observed at 24 hours, 72 hours,
7 and 14 days post-administration. Signs of erythema and eodema were
scored according to the draize technique.
Signs of erythema and oedema were evident at
24 hours, 72 hours, and 7 days. By day 14 all erythema and oedema had
subsided. The mean erythema and oedema scores during the 24 to 72 hour
observation periods were 2.5 and 1.5, respectively. Based on the
conditions of this study, the test material is classified as an
This study received a Klimisch score of 2
and is classified as reliable with restrictions because it is an
acceptable and a well-documented study report.
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