Registration Dossier
Registration Dossier
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EC number: 237-301-3 | CAS number: 13732-62-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to fish.
Key value for chemical safety assessment
Additional information
A guideline study on the acute toxicity of the test substance to fish is available which has been conducted according to DIN 38412 with the test species Leuciscus idus. A static test procedure has been applied and the test organisms have been exposed to the test substance over a period of 96 h. At test termination, a LC50 > 500 mg/L (nominal) was determined [BASF AG 1980].
Supporting information is available from toxicity testing with the test substance's dissociation products morpholine and toluene-4 -sulphonate.
Two publications have been composed on the assessment of the acute toxicity of morpholine to fish. Calamari (1980) conducted its experiment according to IRSA (1973) with the test species Oncorhynchus mykiss over a test period of 96 h with hard and soft test water in a static test system, respectively. At test termination, LC50 values of 180 mg/L (soft water) and 320 mg/L (hard water) were determined. McCain (1976) examined the toxic effects of morpholine to the salt water species Vala mugil engeli under static conditions for 96 h. At the end of the exposure period, a LC50 of 179 mg/L was determined.
For the assessment of toluene-4 -sulphonate there is one guideline study according to OECD 203 available [Habrino Decin 1981]. Test fish of the species Leuciscus idus melanotus were exposed to a 65% solution of the test substance in a static test system. At test termination after 96 h a LC50 > 325 mg/L based on the active ingredient was determined.
Sincethe test substance as well as its dissociation products show effect concentrations > 100 mg/L it can be concluded that the test substance is with high probability acutely not harmful to fish.
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