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EC number: 276-911-4
CAS number: 72829-25-5
acute oral toxicity of FAT 40034 was evaluated in a limit test using Sprague-Dawley
rats according to a methodology similar to OECD Guideline 401. 5 males
and 5 females were administered a single dose of 5000 mg/kg bw orally.
After administration of the compound, the animals were observed for 14
days. Deaths and clinical symptoms were recorded. At the end of the
observation period, surviving animals were killed by exsanguination
under ether anaesthesia and an autopsy performed. No clinical symptoms
were recorded and no deaths occurred. At autopsy no changes caused by
the administration of FAT 40034/A were seen. In
conclusion, the acute oral median lethal dose (LD50) of FAT
40034/A in SD rats of both sexes observed over a period of 14 days is
greater than 5000 mg/kg bw.
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