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EC number: 225-443-9 | CAS number: 4851-50-7
A dose of 2000 mg/kg body weight was tolerated by males and females without toxicologically relevant clinical signs. Locally, a blue discoloration of the treatment area was observed.
The most plausible interpretation is a discoloration by the blue color of the test item (which is not considered a toxicologically relevant effect).
There were no toxicologically significant effects on body weight or body weight development in males and females.
Gross Pathology Findings
The necropsies performed at the end of the study revealed no particular findings.
Groups of 5 male and 5 female Wistar rats received a single dermal dose of 2000 mg/kg body weight of the test item applied semioclclusively for 24 hours.
None of the animals died. A dose of 2000 mg/kg body weight was tolerated by males and females without toxicologically relevant clinical signs. There were no toxicologically significant effects on body weight or body weight development in males and females.
LD50 > 2000 mg/kg bw (rat, male + female)
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