Registration Dossier
Registration Dossier
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EC number: 259-709-0 | CAS number: 55566-30-8
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
OECD Guideline 210, EPA OPPTS 850.1400, GLP, key
study, validity 1:
32d-NOEC (Pimephales promelas) = 0.83 mg/L (mean measured, as main
ingredient) for larval survival and growth.
(For more details please read CSR available in section 13).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.83 mg/L
Additional information
One key study of reliability 1 is available to assess the long-term toxicity of the active substance THPS to fish. This study was performed on the THPS in solution in flow-through conditions, with the freshwater species Pimephales promelas.
The result of this study is expressed in the table below (as main ingredient):
Test method |
Species |
Endpoint / Type of test |
Exposure |
Reliability |
Flag |
Result (NOEC, mg/L) |
Reference |
OECD Guideline 210 and EPA OPPTS 850.1400 |
Pimephales promelas (freshwater species) |
Larval survival and growth / Chronic |
Flow-through, 32 days |
1 |
KS |
0.83 |
Knight, 2002 |
In conclusion, the 32d-NOEC on Pimephales promelas was determined to be 0.83 mg/L.
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