Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

OECD Guideline 202 part 2 (= OECD 211), GLP, key study, validity 1:
21d-NOEC (Daphnia magna) = 0.0242 mg/L (nominal, as main ingredient) for reproduction.

(For more details please read CSR available in section 13).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.024 mg/L

Additional information

One key study of reliability 1 is available to assess the long-term toxicity of the active substance THPS to aquatic invertebrates. This study was performed on the THPS in solution in semi-static conditions, with the freshwater species Daphnia magna.

The result of this study is expressed in the table below (as main ingredient):

Test method


Endpoint / Type of test




Result (lowest NOEC, mg/L)


OECD Guideline 202, part 2 (=OECD 211)

Daphnia magna (freshwater species)

Mortality and Reproduction / Chronic

Semi-staitc, 21 days



0.0242 (reproduction)

Jenkins, 1991e

In conclusion, the 21d-NOEC (reproduction) on Daphnia magna was determined to be 0.0242 mg/L.