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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

No acute toxicity test data were available for exposure of tripropylene glycol butyl ether highers (TPnB-H) to fish.  Therefore, a read across approach was used for short-term toxicity to fish based on test results for tripropylene glycol n-butyl ether and  SYNALOX* 100-50B ( dipropyleneglycol n-butylether initiated alkoxylate, Mw = 1375).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
564 mg/L

Additional information

The 96 hr LC50 value for Poecillia reticulata exposed to TPnB was 564 mg/L, while the 96 hr LC50 value for zebrafish in a study with SYNALOX*100 -50B was report as >104 mg/L. The molecular weights for these two read across substances ranges from 248 (TPnB) to 1375 for SYNALOX*100 -50B. The chemical structure and molecular weight of TPnB highers is closer to TPnB, therefore the TPnB toxicity endpoint was considered to be more accurate for read across.