Registration Dossier
Registration Dossier
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EC number: 500-003-1 | CAS number: 9003-13-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No acute toxicity test data were available for exposure of tripropylene glycol butyl ether highers (TPnB-H) to fish. Therefore, a read across approach was used for short-term toxicity to fish based on test results for tripropylene glycol n-butyl ether and SYNALOX* 100-50B ( dipropyleneglycol n-butylether initiated alkoxylate, Mw = 1375).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 564 mg/L
Additional information
The 96 hr LC50 value for Poecillia reticulata exposed to TPnB was 564 mg/L, while the 96 hr LC50 value for zebrafish in a study with SYNALOX*100 -50B was report as >104 mg/L. The molecular weights for these two read across substances ranges from 248 (TPnB) to 1375 for SYNALOX*100 -50B. The chemical structure and molecular weight of TPnB highers is closer to TPnB, therefore the TPnB toxicity endpoint was considered to be more accurate for read across.
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