Registration Dossier
Registration Dossier
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EC number: 500-003-1 | CAS number: 9003-13-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A 96-hr green algae growth and inhibition test was conducted with Pseudokirchneriella subcapitata to DOWANOL TPnB-H Glycol Ether following OECD 201.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 333 mg/L
- EC10 or NOEC for freshwater algae:
- 93.7 mg/L
Additional information
The effects of DOWANOL TPnB-H Glycol Ether on the growth of Pseudokirchneriella subcapitata under static conditions was determined in a GLP study following OECD 201. The endpoints included growth rate and yield (as biomass). The results are reported as 72- and 96 -hour No-Observed-Effect Loading Rate (NOELR) and Lowest-Observed-Effect Loading Rate (LOELR) as well as 72- and 96 -hour Effect Loading Rates EL10, EL20 and EL50 values. Also, the 24- and 48 -hour EL50 values for yield (biomass) were reported. Endpoints for the 72 and 96 -hour NOELR and LOELR were 62.5 and 125 mg/L. The 72 -hr EL10 for growth rate was 93.7 mg/L followed by the EL20 and EL50 at 129 and 333 mg/L, respectively.
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