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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

An algal study with Pseudokirchneriella subcapitata and an OECD 209 activated sludge inhibition test were available for tripropylene glycol n-butyl ether highers (TPnB-H). The 72 -hr EL10 for algal growth rate was 93.7 mg/L followed by the EL20 and EL50 at 129 and 333 mg/L, respectively. In the sludge inhibition test, the resulting EC50 vlaue was determined to be greater than 1,000 mg/L, the highest concentration tested.

Acute toxicity to aquatic invertebrates and fish was determined using a read-across approach to tripropylene glycol n-butyl ether (TPnB) and SYNALOX. The 48 hr NOEC value for Daphnia magna exposed to TPnB was 1000 mg/L, while the 48 hr EL50 value in a study with SYNALOX*100 -20B was report as >100 mg/L, which was the highest concentration tested. The 96 hr LC50 value for Poecillia reticulata exposed to TPnB was 564 mg/L, while the 96 hr LC50 value for zebrafish in a study with SYNALOX*100 -50B was report as >104 mg/L. The molecular weights for these three read across substances ranges from 248 (TPnB) to 750 for SYNALOX*100 -20B and 1375 for SYNALOX*100 -50B. The chemical structure and molecular weight of TPnB highers is closer to TPnB, therefore the TPnB toxicity endpoints were considered to be more accurate for read across.