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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to birds

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

In accordance with REACH Regulation 1907/2006, Annex X, Column 2, reproductive toxicity tests to birds do not need to be conducted as a large mammalian dataset is available (see toxicological studies). In addition direct and indirect exposure of the soil compartment is unlikely. The substance has little potential to adsorb to soil and is not very persistent. According to the available information about production and processing of the substance, and the uses identified, direct releases of the substance to the terrestrial compartment can be excluded.

Furthermore, there is no wide dispersive use as the chemical is only used in industrial processes. From industrial processes, the release of 4-MHHPA into the sewage is very limited, if not completely negligible, as the chemical is incorporated into a matrix during polymer manufacturing, In the unlikely case that 4-MHHPA will reach sewage, the anhydride group, which represents the single reactive and toxic functional moiety, rapidly hydrolyses to the respective di-acid. Overall, it is expected that 4-MHHPA will not be present in sewage sludge, will not be distributed to sediment, and direct or indirect exposures of the aquatic and terrestrial compartments are unlikely