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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

NOEC: 11 mg/L

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
11 mg/L

Additional information

No aquatic toxicity studies with chronic exposure are available on the registered substance itself. Reliable data on fish are available for two structural analogues of the substance, MTHPA and phthalic anhydride, with determined NOEC values of 100 and 10 mg/L, respectively. The lower NOEC value of 10 mg/L determined for phthalic anhydride was used as suitable read-across value for 4-MHHPA considering a worst case approach. The NOEC from this study was 10 mg/L which, when corrected for differences in molecular weight, results in a calculated NOEC of 11 mg/L for 4 -MHHPA.