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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Description of key information

Partition coefficient (LogPow): 2.09 as methyl-4-hexahydrophthalic anhydride

Partition coefficient (LogD): 1.4 as 1,2-Cyclohexanedicarboxylic acid, 4-methyl- (undissociated)

Partition coefficient (LogD): -3.95 as 1,2-Cyclohexanedicarboxylic acid, 4-methyl- (dissociated, environmental conditions)

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information

Partition coefficients have been investigated using methods in accordance with accepted OECD/EU test and in-silico methods.

A LogPow of 2.09 was determined for methyl-4-hexahydrophthalic anhydride (4-MHHPA)

4-MHHPA is hydrolysed practically instantaneously to 1,2-Cyclohexanedicarboxylic acid, 4-methyl (4-MHHPAc), then for the environmental and PBT assessments, the acid form was considered more significant, with logD= -3.96 at pH= 8 (water, environmental conditions).

Considering all the charge-state forms of 4-MHHPAc dissolved in water and in octanol, a LogD (distribution coefficient) was estimated taking account for the pH dependence of the substance in aqueous solution.