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EC number: 243-072-0
CAS number: 19438-60-9
Algal growth inhibition: ErC50= 135 (127 – 143) mg/L; EyC50 = 81.3 (72.7 – 89.8) mg/L; NOEC = 32.0 mg/L
Algal growth inhibition to the
unicellular freshwater green alga Pseudokirchneriella subcapitata has
been investigated according to OECD/EU test methods. 4
–MHHPA was found to inhibit the growth after 72 hours exposure,
EC50-values with 95 % confidence intervals for inhibition of specific
growth rate (ErC50) and yield (EyC50) being 135 (127 – 143) mg/L and
81.3 (72.7 – 89.8) mg/L, respectively.
In accordance with ECHA guidance on information
requirements and chemical safety assessment, Chapter R.7b: Endpoint
specific guidance, theErC50 endpoint is used in DNEL derivation. This is
because use of values based on biomass cannot be applied to an analysis
of results from a system in exponential growth without logarithmic
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