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EC number: 701-008-3
CAS number: -
No dermal absorption data are available on
S278. In a reliable dermal absorption study on the structurally related
compound, butyl benzyl phthalate (BBP), 14C-labelled BBP
The proportion of the administered dose
found in the tissues and excreta after 7 days was
30% in urine and faeces, 4.6% in muscle,
<0.5% in brain, spinal cord and testis, 0.17% in adipose tissue and
Covered application of 14C-BBP on the shaved
skin of rats (to an area of 1.3 cm2) at 49 mg/kg bw (7.7 mg/cm2) for 7
days resulted in approximately 35% dermal absorption over this period,
equivalent to 5% per day.
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