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EC number: 701-008-3
CAS number: -
The mean estimated log Koc for Santicizer 278 is 5.383.
data is not available for Santicizer 278. As
the log Kow is >3 the adsorption/desorption endpoint cannot be waived.
However, ECHA's Guidance on Information Requirements and Chemical Safety
Assessment R7a Endpoint Specific Guidance (2008) indicates that before
commissioning a new study alternative sources of data (e.g. QSAR) on the
adsorption/desorption potential of a chemical should used.
Soil sorption of non-ionic substances can be
estimated from their log Kow. Several QSAR have been developed that
calculate the Koc of non-polar hydrocarbons on the basis of their log
Kow. Two QSARs (the two methods of KOCWIN, USEPA 2008) have been used to
calculate the log Koc of Santicizer 278. The estimated log Koc are 6.099
and 4.666, and the mean of these values will be used in the risk
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