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EC number: 248-948-6
CAS number: 28299-41-4
No signs of a mutagenic effect after a single oral application of 0.1
ml/kg of the test substance.
Method: 10 mice (5 male + 5 female) received a single oral application
of 0.1 ml/kg bw of the test substance. animals were killed after 24, 48
and 72 hours and bone marrow was reprocessed. 1000 polychromatic
erytrocytes were evaluated and the number of normochromatic erythrocytes
counted. Additionally micronucleated cells per 1000 normochromatic and
polychromatic erythrocytes were determined.
Result: no indication for a mutagenic effect was found. treated animals
revealed no signs of poisoning and survived until sacrifice.
Reference: Herbold (Bayer AG), 1984.
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