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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1987
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Reason / purpose for cross-reference:
reference to other study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
(1984)
Deviations:
no
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
column elution method
Water solubility:
2.8 mg/L
Temp.:
20 °C
pH:
7.5
Water solubility:
2.84 mg/L
Temp.:
20 °C
pH:
7.4

Results at 20 °C

Column 1: 2.8 mg/L

Column 2: 2.84 mg/L

Average: 2.82 mg test item/L of water

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility value was determined experimentally. The water solubility of the substance is slightly soluble with a value of 2.82 mg/L.
Executive summary:

The water solubility of the substance was determined in accordance with the EU method A.6. The average water solubility resulting from two columns was found to be 2.82 mg/L at 20 °C. This indicates that the substance is slightly soluble in water.

Description of key information

The water solubility value was determined experimentally. The water solubility of the substance is slightly soluble with a value of 2.82 mg/L.

Key value for chemical safety assessment

Water solubility:
2.82 mg/L
at the temperature of:
20 °C

Additional information

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