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Environmental fate & pathways

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A number of reported data were available on 1,3-diphenylguanidine from 1960 to 1988. However, data assessment was difficult because the studies were poorly documented. In some of those studies, DPG was noted as rapidly degraded or readily biodegradable but either no sound biodegradation follow-up was performed or no sound detail about the inoculum pre-treatment was given. That is the reason why a full OECD 301D study was commissioned in 2015. This study showed that DPG is readily biodegradable and that no persistent metabolite can be expected.