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EC number: 203-906-6
CAS number: 111-77-3
Substantial condensation of test material was seen in the inlet ducts to
the top dose test chamber. It is possible that there may have been some
exposure to aerosol in the top dose group. The mean daily nominal
concentration was 343ppm, with the difference between this and the
analytical figure due to these condensation losses. Measured and
nominal concentrations at the two lower doses were within 10% of each
In a sub-chronic inhalation toxicity study that closely followed the
requirements of a guideline study, male and female rats were exposed to
2 -(2 -methoxyethoxy)ethanol at concentrations up to and included
saturated vapour concentrations. No changes were seen in any of the
measured parameters, including body weight, haematology, clinical
chemistry, urinalysis and gross and histopathological organ examination
that could be attributed to substance exposure. Based on this result, a
NOAEC of 216ppm or 1060mg/m3 can be established and more importantly, it
can be concluded that there is no hazard evident in rats from any
conceivable exposure to vapour
NOAEC (inhalation, rats) >1060mg/m3 .
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