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Diss Factsheets
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EC number: 203-906-6 | CAS number: 111-77-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC10 (17hr) P. putida >10000mg/l
EC50 (time unknown) P. fluorescens >100mg/l
EC50 (30min) activated sludge >1000, >1995mg/l
EC50 (16hr) sewage microorganisms >5000mg/l
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 10 000 mg/L
Additional information
A reliable study is available in which the bacteria P.putida was exposed to 2 -(2 -methoxyethoxy)ethanol for 17 hours at concentrations up to 10,000mg/l without any inhibition of growth (determined by optical density measurement). This study is considered the most appropriate to use to derive the key parameter. It is supported by two other studies in a weight of evidence approach, both of which used activated sludge respiration inhibition as the end point. Both established no effects at the maximum tested concentrations of 1000 and 1995mg/l respectively. A further study with P. fluorescens did not establish an EC50 up to the maximum tested dose of 100mg/l. All of these studies are supportive of the choice of key parameter. All tests are also in line with the results of the biodegradation studies and the concentrations used in these (see chapter 5.2.1) From the available data, it can be concluded that this substance causes no acute adverse effects to micro-organisms up to concentrations of 10g/l or more.
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