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Four guideline ready biodegradation studies are available to 3 different methods. Two were duplicate determinations to the same protocol. In a closed bottle test, the substance reached 68% degradation after 28 days but did not meet the 10 day window criteria of 60%. The modified sturm test (CO2 evolution) was repeated in duplicate. Both showed degradation of >75% after 28 days but only one met the 10 day window criteria. Since the average of these two results did meet the 10 day criteria, it can be concluded that 2 -(2 -methoxyethoxy)ethanol is readily biodegradable and does meet the 10 day window, although this is marginal. However another study using this method showed rapid and 100% degradation after 28 days. A conclusion of ready biodegradability is also supported by QSAR modelling.

As the substance is identified as readily biodegradable in the screening studies, further biodegradation testing is not scientifically justified.