Registration Dossier
Registration Dossier
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EC number: 202-551-4 | CAS number: 97-00-7
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: few details; short publication.
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- P.J. Dierickx and C. Vanderwielen
- Year:
- 1 986
- Bibliographic source:
- Gluthathione dependent toxicity of the algicide 1-chloro-2,4-dinitrobenzene to Daphnia magna Straus. Bulletin of Environmental Contamination and Toxicology, 1986. 37: p. 629-632.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- ISO 6341 (Water quality - Determination of the Inhibition of the Mobility of Daphnia magna Straus (Cladocera, Crustacea))
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-chloro-2,4-dinitrobenzene
- EC Number:
- 202-551-4
- EC Name:
- 1-chloro-2,4-dinitrobenzene
- Cas Number:
- 97-00-7
- Molecular formula:
- C6H3ClN2O4
- IUPAC Name:
- 1-chloro-2,4-dinitrobenzene
Constituent 1
Test solutions
- Details on test solutions:
- Concentrations from 0.12 to 1.85 mg/l used
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Only adults daphnids used.
20 organisms (4 replicates of 5 individuals each) tested at each concentration
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 225 - 275 mg/l (as CaCO3) and Ca:Mg ratio of 4:1
- Test temperature:
- 19 - 20 ºC
- pH:
- 7 - 7.6
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.85 mg/L
- Remarks on result:
- other: 95
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.59 mg/L
- Remarks on result:
- other: 95
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.66 mg/L
- Remarks on result:
- other: 95
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.49 mg/L
- Remarks on result:
- other: 95
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Deemed to be very toxic towards Daphnia Magna.
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