Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-551-4 | CAS number: 97-00-7
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: few details; short publication.
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- P.J. Dierickx and C. Vanderwielen
- Year:
- 1 986
- Bibliographic source:
- Gluthathione dependent toxicity of the algicide 1-chloro-2,4-dinitrobenzene to Daphnia magna Straus. Bulletin of Environmental Contamination and Toxicology, 1986. 37: p. 629-632.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- ISO 6341 (Water quality - Determination of the Inhibition of the Mobility of Daphnia magna Straus (Cladocera, Crustacea))
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-chloro-2,4-dinitrobenzene
- EC Number:
- 202-551-4
- EC Name:
- 1-chloro-2,4-dinitrobenzene
- Cas Number:
- 97-00-7
- Molecular formula:
- C6H3ClN2O4
- IUPAC Name:
- 1-chloro-2,4-dinitrobenzene
Constituent 1
Test solutions
- Details on test solutions:
- Concentrations from 0.12 to 1.85 mg/l used
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Only adults daphnids used.
20 organisms (4 replicates of 5 individuals each) tested at each concentration
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 225 - 275 mg/l (as CaCO3) and Ca:Mg ratio of 4:1
- Test temperature:
- 19 - 20 ºC
- pH:
- 7 - 7.6
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.85 mg/L
- Remarks on result:
- other: 95
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.59 mg/L
- Remarks on result:
- other: 95
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.66 mg/L
- Remarks on result:
- other: 95
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.49 mg/L
- Remarks on result:
- other: 95
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Deemed to be very toxic towards Daphnia Magna.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
