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EC number: 203-988-3
CAS number: 112-59-4
Five rats of each sex weighing between 200
and 300g were exposed to a statically generated saturated vapour for 6
hours. The vapour was produced by enclosing the test material into a
sealed 120 liter animal chamber and allowing the vapour to equilibrate
for 18 hours (Static condition). Rats were introduced into separate
chambers through gasketted drawers designed to minimize vapour loss.
Oxygen content was continuously monitored and maintained at 20%. Animals
were removed from the chamber after 6 hours of exposure and were
observed for 14 days. Body weights were measured before exposure and 7
and 14 days following exposure. All rats were subjected to necropsy
after the 14 day observation period.
All animals survived the 6 hour exposure. There were no
signs of toxicity or irritancy during or after exposure.
Animals gained weight over the fourteen day observation
period and had normal pathology.
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