Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
203-988-3
CAS no.:
112-59-4
Index number:
Molecular formula:
C10H22O3
SMILES:
CCCCCCOCCOCCO
InChI:
InChI=1S/C10H22O3/c1-2-3-4-5-7-12-9-10-13-8-6-11/h11H,2-10H2,1H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
6
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is harmful in contact with skin and causes serious eye damage.

Breakdown of all 763 C&L notifications submitted to ECHA

Acute Tox. 4 H312 Harmonised Classification
Eye Dam. 1 H318 Harmonised Classification
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 9 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 - 1 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: coating products, lubricants and greases, non-metal-surface treatment products, anti-freeze products, polishes and waxes, adhesives and sealants and leather treatment products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in complex articles, with no release intended: vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and leather (e.g. gloves, shoes, purses, furniture).

This substance is used in the following products: laboratory chemicals, welding & soldering products and pH regulators and water treatment products.

This substance is used in the following areas: scientific research and development and health services.

This substance is used in the following activities or processes at workplace: roller or brushing applications, non-industrial spraying, treatment of articles by dipping and pouring and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: welding & soldering products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: welding & soldering products, coating products and inks and toners.

This substance is used in the following areas: health services and scientific research and development. This substance is used for the manufacture of: electrical, electronic and optical equipment and chemicals.

This substance is used in the following activities or processes at workplace: industrial spraying, roller or brushing applications, treatment of articles by dipping and pouring, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and calendering operations.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as processing aid, of substances in closed systems with minimal release and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Arrow Regulatory (Ireland) Ltd OR1705, Suite 307, No.9 9 Pembroke Street Upper D02 KR83 Dublin 2 Ireland
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • DOW BENELUX B.V. - OR2, Postbus 48 4530 AA Terneuzen Netherlands
  • Heraeus Romania S.R.L. , Str. DN 59, km 8+550m stanga Parcul Industrial INCONTRO 307221 Chisoda Comuna Giroc, jud. Timiş Romania
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • N.V. ASAHI PHOTOPRODUCTS (EUROPE) S.A., Paepsem Business Park Boulevard Paepsem 22 1070 Brussels Belgium

Substance names and other identifiers

diethylene glycol monohexyl ether
C&L Inventory
2,(2-hexiloxietoxi)etanol (pt)
C&L Inventory
2-((2-hexiloxi)etoxi)-etanoldietilenglicol monohexil éter (es)
C&L Inventory
2-(2-esilossietossi)etanolo (it)
C&L Inventory
2-(2-heksil-oksietoksi)etanol (hr)
C&L Inventory
2-(2-heksiloksietoksi) etanols, (lv)
C&L Inventory
2-(2-heksiloksietoksi)etanol (sl)
C&L Inventory
2-(2-heksiloksietoksi)etanolis (lt)
C&L Inventory
2-(2-heksyloksyetoksy)etanol (no)
C&L Inventory
2-(2-Heksyylioksietoksi)etanoli (fi)
C&L Inventory
2-(2-heksüüloksüetoksü)etanool (et)
C&L Inventory
2-(2-hexiloxietoxi) etanol (es)
C&L Inventory
2-(2-hexiloxietoxi)etanol (hu)
C&L Inventory
2-(2-hexyloxyethoxy)ethanol (da)
C&L Inventory
2-(2-hexyloxyéthoxy)éthanol (fr)
C&L Inventory
2-(2-εξυλοξυαιθοξυ)αιθανόλη (el)
C&L Inventory
2-(2-хексилоксиeтокси)етанол (bg)
C&L Inventory
2-[2-(hexyloxi)etoxi]etanol (sv)
C&L Inventory
2-[2-(hexyloxy)ethoxy]ethan-1-ol (cs)
C&L Inventory
2-[2-(hexyloxy)etoxy]etanol (sk)
C&L Inventory
3,6-dioksa-1-dodecanol (no)
C&L Inventory
3,6-dioksa-1-dodekanol (hr)
C&L Inventory
3,6-Dioksa-1-dodekanoli (fi)
C&L Inventory
3,6-dioksa-1-dodekanolis (lt)
C&L Inventory
3,6-dioksa-1-dodekanool (et)
C&L Inventory
3,6-dioksa-1-dodekānols (lv)
C&L Inventory
3,6-dioksadodecan-1-ol (no)
C&L Inventory
3,6-dioksadodekaan-1-ool (et)
C&L Inventory
3,6-dioksadodekan-1-ol (hr)
C&L Inventory
3,6-dioksadodekan-1-olis (lt)
C&L Inventory
3,6-dioksadodekanols-1 (lv)
C&L Inventory
3,6-diossa-1-decanolo (it)
C&L Inventory
3,6-dioxa-1-dodecanol (da)
C&L Inventory
3,6-dioxa-1-dodecanolhexilcarbitol (es)
C&L Inventory
3,6-dioxa-1-dodekanol (cs)
C&L Inventory
3,6-dioxa-1-dodécanol (fr)
C&L Inventory
3,6-Dioxadodecan-1-ol (de)
C&L Inventory
3,6-dioxadodekán-1-ol (hu)
C&L Inventory
3,6-διοξα-1-δωδεκανόλη (el)
C&L Inventory
3,6-диoксa-1-додеканол (bg)
C&L Inventory
3,6-диoксaдодекан-1-ол (bg)
C&L Inventory
DEGHE (bg)
C&L Inventory
diethyleenglycolmonohexylether (nl)
C&L Inventory
Diethylenglycol-Monohexylether (de)
C&L Inventory
diethylenglycolmonohexylether (da)
C&L Inventory
diethylenglykolmonohexylether (cs)
C&L Inventory
dietilen glicol monohexil eter (ro)
C&L Inventory
dietilen glikol monoheksil eter (sl)
C&L Inventory
dietilen-glikol monoheksil-eter (hr)
C&L Inventory
Dietileneglicol monoesiletere (it)
C&L Inventory
dietilenglikolio monoheksileteris (lt)
C&L Inventory
dietilén-glikol-monohexil-éter (hu)
C&L Inventory
dietilēnglikola monoheksilēteris (lv)
C&L Inventory
Dietyleeniglykolin monoheksyylieetteri (fi)
C&L Inventory
dietylenglykolmonoheksyleter (no)
C&L Inventory
dietylenglykolmonohexyleter (sv)
C&L Inventory
dietylénglykol-monohexyléter (sk)
C&L Inventory
dietüleenglükoolmonoheksüüleeter (et)
C&L Inventory
esilcarbitolo (it)
C&L Inventory
eter monoheksylowy glikolu dietylenowego (pl)
C&L Inventory
heksil karbitol (sl)
C&L Inventory
heksil-karbitol (hr)
C&L Inventory
heksilkarbitolis (lt)
C&L Inventory
heksilkarbitols (lv)
C&L Inventory
heksylkarbitol (no)
C&L Inventory
Heksyylikarbitoli (fi)
C&L Inventory
heksüülkarbitool (et)
C&L Inventory
hexil carbitol (ro)
C&L Inventory
hexil-karbitol (hu)
C&L Inventory
hexyl carbitol (fr)
C&L Inventory
hexyl-karbitol (sk)
C&L Inventory
Hexylcarbitol (de)
C&L Inventory
hexylkarbitol (cs)
C&L Inventory
Éter mono-hexílico de dietilenoglicol (pt)
C&L Inventory
éther monohexylique du diéthylène glycol (fr)
C&L Inventory
εξυλοκαρβιτόλη (el)
C&L Inventory
μονοεξυλαιθέρας της διαιθυλενογλυκόλης (el)
C&L Inventory
диетилен гликол монохексилов етер (bg)
C&L Inventory
хексилкарбитол (bg)
C&L Inventory
Ethanol, 2-[2-(hexyloxy)ethoxy]-
Other
2-(2-hexoxyethoxy)ethanol
C&L Inventory
2-(2-hexyloxyethoxy) ethanol
C&L Inventory
2-[2-(Hexan-1-yloxy)ethoxy]ethanol
C&L Inventory
2-[2-(hexyloxy)ethoxy]ethanol
C&L Inventory, Registration dossier
3,6-dioxa-1-dodecanol 3,6-dioxadodecan-1-ol DEGHE diethylene glycol monohexyl ether hexyl carbitol
Registration dossier
Di(ethylene glycol) hexyl ether, Hexyldiglycol
Registration dossier
diethylene glycol monohexyl ether;
C&L Inventory
Ethanol, 2-(2-(hexyloxy)ethoxy)-
C&L Inventory
DIAETHYLENGLYKOL-MONOHEXYLAETHER
Registration dossier
Diethylene glycol hexyl ether
Registration dossier
diethylene glycol mono-hexyl
Registration dossier
DODECAN-1-OL, 3,6-DIOXA-
Registration dossier
HeDG
Registration dossier
Hexyl CARBITOL™ Solvent
Registration dossier
n-Hexoxyethoxyethanol
Registration dossier
n-Hexyl carbitol
Registration dossier
N-HEXYLCARBITOL
Registration dossier
NSC 403666
Registration dossier
Ucar Filmer EHC
Registration dossier
112-59-4
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other
603-175-00-7
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Liquid (100%) [2]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 4 studies submitted
  • 1 study processed
R Boiling point
262.15 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
262 °C

Density

Study results
  • 4 studies submitted
  • 2 studies processed
R Density
0.93 - 0.94 g/cm³ @ 20 °C [2]

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.93

Vapour pressure

Study results
  • 3 studies submitted
  • 1 study processed
R Vapour pressure
0.221 - 99.9 Pa @ 20 - 87.46 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0.221 Pa @ 20 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
1.7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
1.7

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
17 g/L @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
17 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 3 studies submitted
  • 1 study processed
R Flash point
135 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
135 °C

Auto flammability

Study results
  • 2 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
211 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
211 °C

Flammability

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 4
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
8.6 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
8.26 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 1.963 mg/L (1)
Intermittent releases (freshwater) 1 mg/L (1)
Marine water 196 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 10 mg/L (1)
Sediment (freshwater) 10.7 mg/kg sediment dw (1)
Sediment (marine water) 1.07 mg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 995 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 days) 200 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC10 (7 days) 19.63 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 97.58 - 198.31 mg/L [2]
EC10 (72 h) 11.08 - 23.43 mg/L [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (30 min) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 16.3 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 50 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: No hazard identified
EYE Exposure
High hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.1 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 25 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.25 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
High hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 4
Data waiving
no waivers
Study data: dermal absorption
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other 6
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 50 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 4 studies submitted
  • 1 study processed
P/RResults
LD50 3.73 - 4.92 mL/kg bw (rat) [2]
M/CInterpretations of results
Category 5 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
inhalation
  • 3 studies submitted
  • 1 study processed
M/CInterpretations of results
Study cannot be used for classification [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
dermal
  • 3 studies submitted
  • 1 study processed
P/RResults
LD50 2.14 - 2.37 mL/kg bw (rabbit) [2]
M/CInterpretations of results
Category 5 based on GHS criteria [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 3 488 mg/kg bw
Dermal route:
Adverse effect observed LD50 2 001 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irreversible damage)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 3 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 300 - 1 000 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 4 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 41 ppm [1]

Study data: inhalation
Studies with data
Key study 1 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 200 - 2 000 mg/kg bw/day [2]

Study data: dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 300 mg/kg bw/day (subacute, rat)
Dermal route - systemic effects:
No adverse effect observed NOAEL 2 000 mg/kg bw/day (subchronic, rat)
Inhalation route - systemic effects:
Adverse effect observed NOAEC 325 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Study results
Study data: reproduction
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 1 000 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant