Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Numerous experimental studies are available for all trophic levels investigating the short- and long-term effects of Amines, N-C10-C16-alkyltrimethylenedi-, reaction products with chloroacetic acid on species of fish, aquatic invertebrates, algae, and microorganisms.
Short-term toxicity data are available for three trophic levels (aquatic invertebrates, fish and algae). The most sensitive species was freshwater algae Pseudokirchneriella subcapitata with an ErC50(72 h) of 23.7 µg a.i./L (mean measured, OECD guideline 201). In a test according to OECD 203 with fish species Oncorhynchus mykiss an LC50 (96 h) of 207.4 µg a.i./L (mean measured) was derived and in a short-term study according to OECD 202 with Daphnia magna the EC50 (48 h) was determined to be 33.3 µg a.i./L (mean measured).
In long-term toxicity tests, aquatic invertebrates showed the highest sensitivity towards Amines, N-C10-C16-alkyltrimethylenedi-, reaction products with chloroacetic acid compared to fish and algae.
In a study with water flea D. magna (OECD 211), the deduced NOEC value was 2.3 µg a.i./L (TWA measured) based on reproduction. For fish, the 23-day key study (according to OECD 215) resulted in a NOEC of ≥ 52.3 µg a.i./L (mean measured). Neither any significant effect nor any trend was observed in Oncorhynchus mykiss. The study investigating the toxicity to aquatic algae (according to OECD 201) resulted in a NOErC of 9.55 µg a.i./L (mean measured).
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