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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

NOEC >/= 52.3 µg a.i./L; Oncorhynchus mykiss, OECD guideline 215, GLP

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
52.3 µg/L

Additional information

The effect of DOPA-Glycinate (20% a.i., as manufactured) on growth and survival of juvenile rainbow trout (Oncorhynchus mykiss) was tested according to OECD guideline 215 (2000) at nominal concentrations of 4.7, 9.4, 18.8, 37.5 and 75.0 μg a.i./L under flow-through conditions for 28 days.

At mean measured concentrations up to and including 52.3 μg a.i./L, neither any significant effect nor any trend was observed. The fish grew well (203–223% of start weight) during the test and fulfilled the control validity criteria of the OECD Guideline 215 at all treatment levels. As no effect was observed, the NOEC of the test item related to mean measured concentration was determined to be ≥ 52.3 μg a.i./L, representing ≥ 261.5 μg test item per litre.