Registration Dossier
Registration Dossier
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EC number: 224-658-5 | CAS number: 4439-24-1
Endpoint summary
Administrative data
Description of key information
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 2-(2-methylpropoxy)ethanol is not expected to induce skin sensitisation.
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation, other
- Type of information:
- other: expert assessment
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- GLP compliance:
- no
- Type of study:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- Key result
- Remarks on result:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- 2-(2-methylpropoxy)ethanol is not expected to induce skin sensitisation.
- Executive summary:
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 2-(2-methylpropoxy)ethanol is not expected to induce skin sensitisation.
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
Justification for classification or non-classification
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 2-(2-methylpropoxy)ethanol did not meet the criteria for classification according to Regulation (EC) No.1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
