Registration Dossier
Registration Dossier
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EC number: 224-658-5 | CAS number: 4439-24-1
Endpoint summary
Administrative data
Description of key information
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 2-(2-methylpropoxy)ethanol is not expected to induce skin sensitisation.
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation, other
- Type of information:
- other: expert assessment
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- GLP compliance:
- no
- Type of study:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- Key result
- Remarks on result:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- 2-(2-methylpropoxy)ethanol is not expected to induce skin sensitisation.
- Executive summary:
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 2-(2-methylpropoxy)ethanol is not expected to induce skin sensitisation.
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
Justification for classification or non-classification
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 2-(2-methylpropoxy)ethanol did not meet the criteria for classification according to Regulation (EC) No.1272/2008.
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